Switching from Humira (Adalimumab) to Cosentyx (Secukinumab) for treating hidradenitis suppurativa (HS) can be a significant decision. Here are some key points based on the knowledge base:

Humira (Adalimumab)
- Mechanism: Neutralizes tumor necrosis factor alpha (TNF-α), a chemical messenger involved in autoimmune attacks Show Full Answer

Switching from Humira (Adalimumab) to Cosentyx (Secukinumab) for treating hidradenitis suppurativa (HS) can be a significant decision. Here are some key points based on the knowledge base:

Humira (Adalimumab)
- Mechanism: Neutralizes tumor necrosis factor alpha (TNF-α), a chemical messenger involved in autoimmune attacks.
- Administration: After an initial loading dose, administered every week or every other week by subcutaneous injection.
- Side Effects: Common side effects include respiratory infections, headache, redness or irritation at injection sites, and rash. Rare but serious side effects include severe allergic reactions, potentially fatal infections, new or worsening heart failure, lupus-like syndrome, demyelinating disease, and increased risk for certain types of cancer such as lymphoma.

Cosentyx (Secukinumab)
- Mechanism: Inhibits interleukin 17A, a chemical messenger involved in HS inflammation.
- Administration: Given every four weeks by subcutaneous injection, may be administered every two weeks if the body doesn’t respond well enough.
- Side Effects: Common side effects include cold symptoms, upper respiratory tract infections, and diarrhea. Rare but serious side effects include severe infections, inflammatory bowel disease, and hypersensitivity reactions.

Reasons for Switching
- Efficacy: If Humira is not providing sufficient relief or if the body is not responding well.
- Side Effects: If experiencing severe or intolerable side effects from Humira.
- Doctor's Recommendation: Based on medical evaluation and history.

Results
- Varied: Results can vary from person to person. Some may find better relief with Cosentyx, while others may not.

For more detailed personal experiences, you might want to visit the respective treatment pages or forums on myHSteam:
- [Humira](https://www.myHSteam.com/treatments/humira)
- [Cosentyx](https://www.myHSteam.com/treatments/cosentyx)

Always consult with your healthcare provider before making any changes to your treatment plan.

 This AI-generated response comes from myHSteam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

Cosentyx (Secukinumab) for Hidradenitis suppurativa | myHSteam

Humira (Adalimumab) for Hidradenitis suppurativa | myHSteam